There is evidence that problem-based learning (PBL) is an effective approach to teach team and problem-solving skills, but also to acquire content knowledge. However, there is hardly any literature about using PBL in philosophy classes. One problem is that PBL is resource intensive because a facilitator is needed for each group of students to support learning efforts and monitor group dynamics. In order to establish more PBL classes, the question is whether PBL can be provided without the need for facilitators. (...) We present a combination of five strategies—among them the collaborative argument visualization software AGORA-net—to replace facilitators. Additionally, we present evidence that these strategies are sufficient to provide a PBL experience that achieves intended learning goals in an ethics class and is satisfying for students without facilitators. (shrink)

They use high-tech equipment, chemical analyses, sampling strategies, and other modern means to gain a better understanding of why and how cultures change. Using the study of the Maya as a test case, Jeremy Sabloff shows how the exciting transformation of archaeology is shedding new light on past civilizations.

This article examines the question of how can museum professionals and the interested public resolve the competing claims of traditional ownership and continuing scientific research in relation to museum collections.

In May 1973 a new collaboration between NASA, the Indian Health Service, and the Lockheed Missiles and Space Company promised to transform the way members of the Papago (now Tohono O’odham) Tribe of southern Arizona accessed modern medicine. Through a system of state-of-the-art microwave relays, slow-scan television links, and Mobile Health Units, the residents of the third-largest American Indian reservation began to access physicians remotely via telemedical encounters instead of traveling to distant hospitals. Examining the history of the STARPAHC (Space (...) Technology Applied to Rural Papago Advanced Health Care) project from the perspective of NASA and its contractors, from the perspective of the Indian Health Service, and from the perspective of O’odham engineers and health professionals offers a new focus, emphasizing the American Indian reservation as a site of medical research and technological development in the late twentieth century, with specific attention to the promise of information technology to address health disparities and the role of American Indians as actors in the late twentieth-century history of science, technology, and medicine. (shrink)

In November of 1959, William Bean published in the Archives of Internal Medicine a scathing review of Félix Martí-Ibañez’s Centaur: Essays on the History of Medical Ideas. Martí-Ibañez and Bean were two of the leading exponents of the importance of medical humanism during a formative period from the 1950s through the 1970s. But the two physicians differed fundamentally in their views of the ideal relationships among the pharmaceutical industry, the medical profession, and the medical humanities. We situate Bean’s review within (...) its historical context, shedding light on the history and diverging uses of the medical humanities. (shrink)

A national survey on researchers’ experiences with their institutional review boards (IRBs) is presented, focused exclusively on social and behavioral researchers. A wide range of experiences is apparent in the data, especially in terms of turnaround time for submitted protocols, incidence of data collection without prior IRB approval, and stated reasons for "going solo." Sixty-two percent felt that the turnaround time they typically experience is "reasonable," and 44% said they had not experienced long delays in obtaining approval. However, 48% of (...) respondents reported either conducting a project without IRB approval or modifying an existing project without IRB approval, with anticipated time for approval being the dominant reason offered for doing so. This adds a new dimension to the widely discussed "national IRB crisis" (e.g., Illinois White Paper, 2005). The article concludes with 2 preliminary recommendations for IRB reform. (shrink)

Biomedical and behavioral research may affect strongly held social values and thereby create significant controversy over whether such research should be permitted in the first place. Institutional review boards responsible for protecting the rights and welfare of participants in research are sometimes faced with review of protocols that have significant implications for social policy and the potential for negative social consequences. Although IRB members often raise concerns about potential long-term social implications in protocol review, federal regulations strongly discourage IRBs from (...) considering them in their decisions. Yet IRBs often do consider the social implications of research protocols and sometimes create significant delays in initiating or even prevent such research. The social implications of research are important topics for public scrutiny and professional discussion. This article examines the reasons that the federal regulations preclude IRBs from assessing the social risks of research, and examines alternative approaches that have been used with varying success by national advisory groups to provide such guidance. The article concludes with recommendations for characteristics of a national advisory group that could successfully fulfill this need, including sustainability, independence, diverse and relevant expertise, and public transparency. (shrink)

This paper forms part of a wider campaign: to deny pointillisme, the doctrine that a physical theory's fundamental quantities are defined at points of space or of spacetime, and represent intrinsic properties of such points or point-sized objects located there; so that properties of spatial or spatiotemporal regions and their material contents are determined by the point-by-point facts. More specifically, this paper argues against pointillisme about the concept of velocity in classical mechanics; especially against proposals by Tooley, Robinson and Lewis. (...) A companion paper argues against pointillisme about -geometry, as proposed by Bricker. To avoid technicalities, I conduct the argument almost entirely in the context of "Newtonian" ideas about space and time, and the classical mechanics of point-particles, i.e. extensionless particles moving in a void. But both the debate and my arguments carry over to relativistic physics. Introduction The wider campaign 2.1 Connecting physics and metaphysics 2.1.1 Avoiding controversy about the intrinsic–extrinsic distinction 2.1.2 Distinction from three mathematical distinctions 2.2 Classical mechanics is not pointilliste, and can be perdurantist 2.2.1 Two versions of pointillisme 2.2.2 Two common claims 2.2.3 My contrary claims 2.3 In more detail... 2.3.1 Four violations of pointillisme 2.3.2 For perdurantism Velocity as intrinsic? 3.1 Can properties represented by vectors be intrinsic to a point? 3.2 Orthodox velocity is extrinsic but local 3.2.1 A question and a debate 3.2.2 The verdict 3.3 Against intrinsic velocity 3.3.1 A common view—and a common problem 3.3.2 Tooley's proposal and his arguments 3.3.3 Tooley's further discussion "Shadow velocities": Lewis and Robinson 4.1 The proposal 4.2 Criticism: the vector field remains unspecified 4.3 Avoiding the presupposition of persistence, using Hilbert's symbol 4.4 Comparison with Robinson and Lewis. (shrink)

Theories of children's developing understanding of mind tend to emphasize either individualistic processes of theory formation, maturation, or introspection, or the process of enculturation. However, such theories must be able to account for the accumulating evidence of the role of social interaction in the development of social understanding. We propose an alternative account, according to which the development of children's social understanding occurs within triadic interaction involving the child's experience of the world as well as communicative interaction with others about (...) their experience and beliefs (Chapman 1991; 1999). It is through such triadic interaction that children gradually construct knowledge of the world as well as knowledge of other people. We contend that the extent and nature of the social interaction children experience will influence the development of children's social understanding. Increased opportunity to engage in cooperative social interaction and exposure to talk about mental states should facilitate the development of social understanding. We review evidence suggesting that children's understanding of mind develops gradually in the context of social interaction. Therefore, we need a theory of development in this area that accords a fundamental role to social interaction, yet does not assume that children simply adopt socially available knowledge but rather that children construct an understanding of mind within social interaction. Key Words: language; Piaget; social interaction; theories of mind; Vygotsky; Wittgenstein. (shrink)

Empirical research in bioethics can be defined as the application of research methods in the social sciences to the direct examination of issues in [bioethics]. As such, empirical work is a form of descriptive ethics, focused on describing a particular state of affairs that has some moral or ethical relevance. For example, empirical research can help to describe cultural beliefs about the appropriateness of providing health-related information, such as the diagnosis of a life-threatening illness, which informs deliberations about the extent (...) to which it is morally important for clinicians to provide comprehensive information to patients in different cultural contexts. Similarly, empirical research can delineate popular attitudes and experiences related to contentious issues such as abortion, cloning, stem-cell research, and physician-assisted suicide to enlighten discussions and policy formulations regarding them. (shrink)

In previous work, I described several examples combining reduction and emergence: where reduction is understood a la Ernest Nagel, and emergence is understood as behaviour that is novel. Here, my aim is again to reconcile reduction and emergence, for a case which is apparently more problematic than those I treated before: renormalization. My main point is that renormalizability being a generic feature at accessible energies gives us a conceptually unified family of Nagelian reductions. That is worth saying since philosophers tend (...) to think of scientific explanation as only explaining an individual event, or perhaps a single law, or at most deducing one theory as a special case of another. Here we see a framework in which there is a space of theories endowed with enough structure that it provides a family of reductions. (shrink)

Abstract:Recently, the idea that every hypothetical imperative must somehow be ‘backed up’ by a prior categorical imperative has gained a certain influence among Kant interpreters and ethicists influenced by Kant. Since instrumentalism is the position that holds that hypothetical imperatives can by themselves and without the aid of categorical imperatives explain all valid forms of practical reasoning, the influential idea amounts to a rejection of instrumentalism as internally incoherent. This paper argues against this prevailing view both as an interpretation of (...) Kant and as philosophical understanding of practical reason. In particular, it will be argued that many of the arguments that claim to show that hypothetical imperatives must be backed up by categorical imperatives mistakenly assume that the form of practical reasoning must itself occur as a premise within the reasoning. An alternative to this assumption will be offered. I will conclude that while instrumentalism may well be false, there is no reason to believe it is incoherent. (shrink)

Crowdfunding websites allow users to post a public appeal for funding for a range of activities, including adoption, travel, research, participation in sports, and many others. One common form of crowdfunding is for expenses related to medical care. Medical crowdfunding appeals serve as a means of addressing gaps in medical and employment insurance, both in countries without universal health insurance, like the United States, and countries with universal coverage limited to essential medical needs, like Canada. For example, as of 2012, (...) the website Gofundme had been used to raise a total of 8.8 million dollars for seventy-six hundred campaigns, the majority of which were health related. This money can make an important difference in the lives of crowdfunding users, as the costs of unexpected or uninsured medical needs can be staggering. In this article, I offer an overview of the benefits of medical crowdfunding websites and the ethical concerns they raise. I argue that medical crowdfunding is a symptom and cause of, rather than a solution to, health system injustices and that policy-makers should work to address the injustices motivating the use of crowdfunding sites for essential medical services. Despite the sites’ ethical problems, individual users and donors need not refrain from using them, but they bear a political responsibility to address the inequities encouraged by these sites. I conclude by suggesting some responses to these concerns and future directions for research. (shrink)

Human subject trials of pharmaceuticals in low and middle income countries have been associated with the moral wrong of exploitation on two grounds. First, these trials may include a placebo control arm even when proven treatments for a condition are in use in other parts of the world. Second, the trial researchers or sponsors may fail to make a successful treatment developed through the trial available to either the trial participants or the host community following the trial.Many commentators have argued (...) that a single form of exploitation takes place during human subject research in LMICs. These commentators do not, however, agree as to what kind of moral wrong exploitation is or when exploitation is morally impermissible. In this paper, I have two primary goals. First, I will argue for a taxonomy of exploitation that identifies three distinct forms of exploitation. While each of these forms of exploitation has its critics, I will argue that they can each be developed into plausible accounts of exploitation tied to different vulnerabilities and different forms of wrongdoing. Second, I will argue that each of these forms of exploitation can coexist in single situations, including human subject trials of pharmaceuticals. This lesson is important, since different forms of exploitation in a single relationship can influence, among other things, whether the relationship is morally permissible. (shrink)

We have two aims. The main one is to expound the idea of renormalization in quantum field theory, with no technical prerequisites. Our motivation is that renormalization is undoubtedly one of the great ideas—and great successes--of twentieth-century physics. Also it has strongly influenced in diverse ways, how physicists conceive of physical theories. So it is of considerable philosophical interest. Second, we will briefly relate renormalization to Ernest Nagel's account of inter-theoretic relations, especially reduction. One theme will be a contrast between (...) two approaches to renormalization. The old approach, which prevailed from ca. 1945 to 1970, treated renormalizability as a necessary condition for being an acceptable quantum field theory. On this approach, it is a piece of great good fortune that high energy physicists can formulate renormalizable quantum field theories that are so empirically successful. But the new approach to renormalization explains why the phenomena we see, at the energies we can access in our particle accelerators, are described by a renormalizable quantum field theory. For whatever non-renormalizable interactions may occur at yet higher energies, they are insignificant at accessible energies. Thus the new approach explains why our best fundamental theories have a feature, viz. renormalizability, which the old approach treated as a selection principle for theories. That is worth saying since philosophers tend to think of scientific explanation as only explaining an individual event, or perhaps a single law, or at most deducing one theory as a special case of another. Here we see a framework in which there is a space of theories. And this framework is powerful enough to deduce that what seemed “manna from heaven” is to be expected: the good fortune is generic. We also maintain that universality, a concept stressed in renormalization theory, is essentially the familiar philosophical idea of multiple realizability; and that it causes no problems for reductions of a Nagelian kind. (shrink)

Medical tourism (MT) can be conceptualized as the intentional pursuit of non-emergency surgical interventions by patients outside their nation of residence. Despite increasing popular interest in MT, the ethical issues associated with the practice have thus far been under-examined. MT has been associated with a range of both positive and negative effects for medical tourists' home and host countries, and for the medical tourists themselves. Absent from previous explorations of MT is a clear argument of how responsibility for the harms (...) of this practice should be assigned. This paper addresses this gap by describing both backward looking liability and forward looking political responsibility for stakeholders in MT. We use a political responsibility model to develop a decision-making process for individual medical tourists and conclude that more information on the effects of MT must be developed to help patients engage in ethical MT. (shrink)

Abstract: This paper assesses the Everettian approach to the measurement problem, especially the version of that approach advocated by Simon Saunders and David Wallace. I emphasise conceptual, indeed metaphysical, aspects rather than technical ones; but I include an introductory exposition of decoherence. In particular, I discuss whether---as these authors maintain---it is acceptable to have no precise definition of 'branch' (in the Everettian kind of sense). (A version of this paper will appear in a CTNS/Vatican Observatory volume on Quantum Theory and (...) Divine Action, ed. Robert Russell et al.). (shrink)

I discuss various formulations of stochastic Einstein locality (SEL), which is a version of the idea of relativistic causality, that is, the idea that influences propagate at most as fast as light. SEL is similar to Reichenbach's Principle of the Common Cause (PCC), and Bell's Local Causality. My main aim is to discuss formulations of SEL for a fixed background spacetime. I previously argued that SEL is violated by the outcome dependence shown by Bell correlations, both in quantum mechanics and (...) in quantum field theory. Here I reassess those verdicts in the light of some recent literature which argues that outcome dependence does not violate the PCC. I argue that the verdicts about SEL still stand. Finally, I briefly discuss how to formulate relativistic causality if there is no fixed background spacetime. (shrink)

This paper expounds the modern theory of symplectic reduction in finite-dimensional Hamiltonian mechanics. This theory generalizes the well-known connection between continuous symmetries and conserved quantities, i.e. Noether's theorem. It also illustrates one of mechanics' grand themes: exploiting a symmetry so as to reduce the number of variables needed to treat a problem. The exposition emphasises how the theory provides insights about the rotation group and the rigid body. The theory's device of quotienting a state space also casts light on philosophical (...) issues about whether two apparently distinct but utterly indiscernible possibilities should be ruled to be one and the same. These issues are illustrated using ``relationist'' mechanics. (shrink)

“Now, in calm weather, to swim in the open ocean is as easy to the practised swimmer as to ride in a spring-carriage ashore. But the awful lonesomeness is intolerable. The intense concentration of self in the middle of such a heartless immensity, my God! who can tell it? Mark, how when sailors in a dead calm bathe in the open sea—mark how closely they hug their ship and only coast along her sides.” (Herman Melville, Moby Dick, Chapter 94).

If unremunerated blood donors are willing to participate, and if the use of them is economical from the perspective of those collecting blood, I can see no objection to their use. But there seems to me no good reason, moral or practical, why they should be used. The system of paid plasmapheresis as it currently operates in the United States and in Canada would seem perfectly adequate, and while there may always be ways in which the safety and efficiency of (...) supply could be increased, there seems no reason whatever to think that there would be an improvement if the current system changed so as to rely entirely on unpaid donors. Further, given the adequacy of paid plasmapheresis, I could see no problem if the collection of whole blood were to take place on a similar, fully-commercial, basis. Such a view is controversial. To argue for it, this paper offers just one strand in a complex argument: a critique of Richard Titmuss’s Gift Relationship, which holds an iconic position in the critical literature on the paid provision of blood. As I conclude: all told, there seems no good basis for rejecting supply of whole blood for money—let alone the supply of blood plasma. (shrink)

The rotating discs argument against perdurantism has been mostly discussed by metaphysicians, though the argument of course appeals to ideas from classical mechanics, especially about rotation. In contrast, I assess the RDA from the perspective of the philosophy of physics. I argue for three main conclusions. The first conclusion is that the RDA can be formulated more strongly than is usually recognized: it is not necessary to ‘imagine away’ the dynamical effects of rotation. The second is that in general relativity, (...) the RDA fails because of frame-dragging. The third conclusion is that even setting aside general relativity, the strong formulation of the RDA can after all be defeated, namely, by the perdurantist taking objects in classical mechanics to have only temporally extended temporal parts, which immediately blocks the RDA. Admittedly, this version of perdurantism defines persistence in a weaker sense of ‘definition’ than pointilliste versions that aim to define persistence assuming only instantaneous temporal parts. But I argue that temporally extended temporal parts can do the jobs within the endurantism– perdurantism debate that the perdurantist wants temporal parts to do and are supported by both classical and quantum mechanics. Introduction The story so far 2.1 The RDA 2.2 Intrinsic properties and the idea of velocity 2.2.1 The intrinsic–extrinsic distinction 2.2.2 Velocity to the rescue? 2.3 ‘Naturalism’ 2.4 The accompaniments of rotation 2.5 Two kinds of reply: against the consensus Describing rotation 3.1 Rotation is kinematic 3.2 Beware of rigidity 3.3 An improved RDA: allowing the actual accompaniments 3.4 The RDA fails in general relativity Perdurantism without tears: the classical case 4.1 Rejecting instantaneous temporal parts 4.2 Replying to the RDA 4.2.1 ‘Kinematics’ 4.2.2 ‘Dynamics’ 4.2.3 An ‘anti-pointilliste’ objection and reply 4.3 Intrinsic properties of non-instantaneous temporal parts 4.3.1 Can the perdurantist appeal to them? 4.3.2 Temporal intrinsicality at an instant is rare 4.3.3 A better reason for temporal intrinsicality 4.4 Non-instantaneous parts can do the jobs 4.4.1 Humean supervenience revisited 4.4.2 The problem of change 4.4.3 Puzzles of coincidence 4.5 Instantaneous velocity is hardly extrinsic Support from decoherence in quantum theory 5.1 Classical and quantum: relativizing the intrinsic–extrinsic distinction 5.1.1 Unitarity: momentum as temporally intrinsic 5.2 Position and existence as nomically extrinsic. (shrink)

Although the pedagogy literature indicates significant relationships between cheating intentions and both personal and situational factors, no published research has examined the joint effect of personal moral philosophy and perceived moral intensity components on students’ cheating intentions. Hence, a structural equation model that relates magnitude of consequences, relativism, and idealism to willingness to cheat, is developed and tested. Using data from undergraduate business students, the empirical results provide insight into these relationships and evidence of mediation for magnitude of consequences on (...) idealism and students’ cheating intentions. Implications for educators are offered. (shrink)

This paper is about the metaphysical debate whether objects persist over time by the selfsame object existing at different times (nowadays called “endurance” by metaphysicians), or by different temporal parts, or stages, existing at different times (called “perdurance”). I aim to illuminate the debate by using some elementary kinematics and real analysis: resources which metaphysicians have, surprisingly, not availed themselves of. There are two main results, which are of interest to both endurantists and perdurantists. (1) I describe a precise formal (...) equivalence between the way that the two metaphysical positions represent the motion of the objects of classical mechanics (both point-particles and continua). (2) I make precise, and prove a result about, the idea that the persistence of objects moving in a void is to be analysed in terms of tracking the continuous curves in spacetime that connect points occupied by matter. The result is entirely elementary: it is a corollary of the Heine–Borel theorem. (shrink)

Virtually every figure in the climate justice literature agrees that states are presently failing to discharge their duties to take action on climate change. Few, however, have attempted to think through what follows from that fact from a moral point of view. In Climate Justice Beyond the State, Lachlan Umbers and Jeremy Moss argue that states’ failures to take action on climate change have important implications for the duties of the most important actors states contain within them – sub-national (...) political communities, corporations, and individuals – actors that have been largely neglected in the climate justice literature, to date. Sub-national political communities and corporations, they argue, have duties to immediately, aggressively, and unilaterally reduce their emissions. Individuals, on the other hand, have duties to help promote collective action on climate change. Along the way, they contribute to a range of important contemporary debates, including those over the nature of collective duties, what agents are required to do under conditions of partial compliance, and the requirements of fairness. Targeted at academic philosophers working on climate justice, this book will also be of great interest to students and scholars of global justice, applied ethics, political philosophy, and environmental humanities. (shrink)

Complementary and alternative medicine is used by many in hopes of achieving important health-related goals. Survey data indicate that 42 percent of the U.S. population uses CAM, accounting for 629 million “office” visits a year and expenditures of 27 billion dollars. This high prevalence of use calls for a careful evaluation of CAM so as to ensure the well-being of those using its modalities. Such an evaluation would obviously include assessments of the safety and efficacy of particular approaches, the training (...) and integrity of practitioners, and the appropriateness of modalities for different conditions or uses. Given the lack of published data concerning many of these aspects of CAM, the likely unfamiliarity of its practitioners to the approaches available to clinicians practicing modern scientific medcine, and the need to respect the unique preferences of persons seeking assistance with achieving health-related goals, it is also important to assess the potential roles of informed consent for the use of CAM. Examining such roles is the central task of this paper. (shrink)

This paper describes an AFOSR-supported basic research program that focuses on developing a new framework for combining hard with soft data in order to improve space situational awareness. The goal is to provide, in an automatic and near real-time fashion, a ranking of possible threats to blue assets (assets trying to be protected) from red assets (assets with hostile intentions). The approach is based on Conceptual Spaces models, which combine features from traditional associative and symbolic cognitive models. While Conceptual Spaces (...) are revolutionary, they lack an underlying mathematical framework. Several such frameworks have attempted to represent Conceptual Spaces, but by far the most robust is the model developed by Holender. His model utilizes integer linear programming in order to obtain an overall similarity value between observations and concepts that support the formation of hypotheses. This paper will describe a method for building Conceptual Spaces models for threats that utilizes ontologies as a means to provide a clear semantic foundation for this inferencing process; in particular threat ontologies and space domain ontologies are developed and employed in this approach. A space situational awareness use-case is presented involving a kinetic kill scenario and results are shown to assess the performance of this fusion-based inferencing framework. (shrink)

Rationale One's understanding of medical progress – what it is, how it is pursued and how it is assessed – may be deeply dependent on one's understanding of the metaphysics of medicine, and of diseases in particular. -/- Aims and Objectives In this paper I present a new account of the nature of diseases, neither realist nor constructivist, and describe what progress in medicine looks like if we understand diseases in this way. -/- Conclusions This new account, Constructive Realism, may (...) provide a better account of medicine than either realism or constructivism. (shrink)

Although COVID-19 vaccines are free and readily available in the United States, many healthcare workers remain unvaccinated, potentially exposing their patients to a life-threatening pathogen. This paper reviews the ethical and legal factors surrounding patient requests to limit their care teams exclusively to vaccinated providers. Key factors that shape policy in this area include patient autonomy, the rights of healthcare workers, and the duties of healthcare institutions. Hospitals must also balance the rights of interested parties in the context of logistical (...) constraints, equity, and public health considerations. (shrink)

I reject Norton and Earman's hole argument that spacetime substantivalism is incompatible with determinism. I reconcile these both technically and philosophically. There is a technical definition of determinism that is not violated by pairs of models of the kind used in the hole argument. And technicalities aside, the basic idea of determinism is not violated if we claim that at most one of the two models represents a possible world. This claim can be justified either by metrical essentialism, or by (...) denying transworld identity for points: I prefer the latter. (shrink)

Political Imaginaries in Question Content Type Journal Article Pages 5-11 Authors Suzi Adams, School of Social and Policy Studies, Flinders University, Adelaide, Australia Jeremy C. A. Smith, School of Education and Arts, University of Ballarat, Victoria, Australia Ingerid S. Straume, University of Oslo Library, University of Oslo, Norway Journal Critical Horizons: A Journal of Philosophy & Social Theory Online ISSN 1568-5160 Print ISSN 1440-9917 Journal Volume Volume 13 Journal Issue Volume 13, Number 1 / 2012.

This paper forms part of a wider campaign: to deny pointillisme. That is the doctrine that a physical theory's fundamental quantities are defined at points of space or of spacetime, and represent intrinsic properties of such points or point-sized objects located there; so that properties of spatial or spatiotemporal regions and their material contents are determined by the point-by-point facts. More specifically, this paper argues against pointillisme about the structure of space and-or spacetime itself, especially a paper by Bricker (1993). (...) A companion paper argues against pointillisme in mechanics, especially about velocity; it focusses on Tooley, Robinson and Lewis. To avoid technicalities, I conduct the argument almost entirely in the context of ``Newtonian'' ideas about space and time. But both the debate and my arguments carry over to relativistic, and even quantum, physics. (shrink)

Frankfurt-type examples seem to show that agents can be morally responsible for their actions and omissions even if they could not have done otherwise. Fischer and Ravizza's influential account of moral responsibility is largely based on such examples. I examine a problem with their account of responsibility in cases where we fail to act. The solution to this problem has a surprising and far reaching implication concerning the construction of successful Frankfurt-type examples. I argue that the role of the counterfactual (...) intervener in such examples can only be filled by a rational agent. (shrink)

Criticisms of the traditional clinical research pathway and its extensive oversight often focus on proposals for deregulation or assert that as in clinical treatment, clinical research should always offer benefit to patient-subjects. Proponents of medical innovation take a different, middle path, arguing that innovation is distinguishable from both research and treatment. This article considers this third pathway by examining stem cell-based innovation.Stem cell-based medical innovation is one pathway toward clinical translation. In fact, such an approach was taken in developing umbilical (...) cord blood transplantation, which is now widely viewed as a safe and effective means for treating a range of malignant and non-malignant conditions. While the Guidelines for the Clinical Translation of Stem Cells created by the International Society for Clinical Research provide an approach to clinical translation that involves “responsible innovation” as an alternative to clinical research, there are at least four sets of unanswered questions regarding the use of an innovation pathway in this context that warrant careful attention. (shrink)

The ambition of this volume is twofold: to provide a comprehensive overview of the field and to serve as an indispensable reference work for anyone who wants to work in it. For example, any philosopher who hopes to make a contribution to the topic of the classical-quantum correspondence will have to begin by consulting Klaas Landsman’s chapter. The organization of this volume, as well as the choice of topics, is based on the conviction that the important problems in the philosophy (...) of physics arise from studying the foundations of the fundamental theories of physics. It follows that there is no sharp line to be drawn between philosophy of physics and physics itself. Some of the best work in the philosophy of physics is being done by physicists, as witnessed by the fact that several of the contributors to the volume are theoretical physicists: viz., Ellis, Emch, Harvey, Landsman, Rovelli, ‘t Hooft, the last of whom is a Nobel laureate. Key features - Definitive discussions of the philosophical implications of modern physics - Masterly expositions of the fundamental theories of modern physics - Covers all three main pillars of modern physics: relativity theory, quantum theory, and thermal physics - Covers the new sciences grown from these theories: for example, cosmology from relativity theory; and quantum information and quantum computing, from quantum theory - Contains special Chapters that address crucial topics that arise in several different theories, such as symmetry and determinism - Written by very distinguished theoretical physicists, including a Nobel Laureate, as well as by philosophers - Definitive discussions of the philosophical implications of modern physics - Masterly expositions of the fundamental theories of modern physics - Covers all three main pillars of modern physics: relativity theory, quantum theory, and thermal physics - Covers the new sciences that have grown from these theories: for example, cosmology from relativity theory; and quantum information and quantum computing, from quantum theory - Contains special Chapters that address crucial topics that arise in several different theories, such as symmetry and determinism - Written by very distinguished theoretical physicists, including a Nobel Laureate, as well as by philosophers. (shrink)

I extract some philosophical morals from some aspects of Lagrangian mechanics. One main moral concerns methodology: Lagrangian mechanics provides a level of description of phenomena which has been largely ignored by philosophers, since it falls between their accustomed levels---``laws of nature'' and ``models''. Another main moral concerns ontology: the ontology of Lagrangian mechanics is both more subtle and more problematic than philosophers often realize. The treatment of Lagrangian mechanics provides an introduction to the subject for philosophers, and is technically elementary. (...) In particular, it is confined to systems with a finite number of degrees of freedom, and for the most part eschews modern geometry. (shrink)

The 1-consistency of arithmetic is shown to be equivalent to the existence of fixed points of a certain type of update procedure, which is implicit in the epsilon-substitution method.